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OBJECTIVES
Objectives of the STriTuVaD project:
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Assessment of the computational modelling framework to simulate the human immune system complex dynamics at large scale;
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Development of the general modelling framework and integration of the following modules of simulation:
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the tuberculosis – immune system interaction;
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the effects of antibiotics therapy in patients with active tuberculosis;
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immunity induced by the tuberculosis vaccines.
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Set-up of the library of virtual patients using data of real patients enrolled for the clinical trial;
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Set-up of the library of virtual patients and run of an empowered in silico-augmented adaptive Bayesian clinical trial;
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In silico trial framework final release.
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