Objectives

Objectives of the STriTuVaD project:

Assessment of the computational modelling framework to simulate the human immune system complex dynamics at large scale;
Development of the general modelling framework and integration of the following modules of simulation:
- the tuberculosis – immune system interaction;
- the effects of antibiotics therapy in patients with active tuberculosis;
- immunity induced by the tuberculosis vaccines.
Set-up of the library of virtual patients using data of real patients enrolled for the clinical trial;
Set-up of the library of virtual patients and run of an empowered in silico-augmented adaptive Bayesian clinical trial;
In silico trial framework final release.